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ImmunoDefence
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A vaccine that is capable of delivering a double whammy against AIDS-causing human immunodeficiency virus by both providing immunity against the infection while at the same time destroying cells infected by the virus is ready for clinical trials, a group of Russian researchers announced today.

The team from Vector State Scientific Center of Virology and Biotechnology, Kol’tsovo, Novosibirsk first reported their research on the CombiHIVvac in the journal Doklady Biochemistry and Biophysics in May 2007.

The vaccine is an artificial virus-like particle whose outer casing consists of the TBI (T- and B cell epitopes containing immunogen) protein constructed by the researchers combined with the polyglucin protein.Read more...Collapse )

Source: http://aids.immunodefence.com/2007/07/hiv_vaccine_ready_for_clinical.html
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Novartis has demonstrated its commitment to the vaccine market with a $500 million (600 million Swiss francs) global licensing deal for Switzerland's Cytos Biotechnology's anti-smoking vaccine. Cytos gains 35 million Swiss francs up front for CYT002-NicQb, which is scheduled to go into late-stage trials in 2008. The rest of the money will be paid in scheduled milestones for a successful development program.
Novartis takes over all development costs and responsibilities. NicQb works by spurring the development of antibodies that attach to nicotine molecules, making them too big to penetrate the blood-brain barrier,thereby reducing nicotine stimulation.

"The vaccine market, including therapeutic vaccines, represents an increasingly attractive segment of the health care market and is an additional source of growth for large pharmaceutical companies," comments Dr. Mark Dyer, EVP Business Development of Cytos Biotechnology.
(source)
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By Maggie Mahar, The Health Care Blog

Merck announced that it is no longer going to try to persuade states to make its new $360 cervical cancer vaccine mandatory for all pre-teens. (At least, not publicly). The company wouldn't divulge how much it has spent, to date, on its lobbying campaign.

Virtually everyone has heard about "Gardasil". Planned Parenthood backs it. Women in Government extols its virtues. (Both organizations receive significant contributions from Merck). Not long ago, a glowing New YorkTimes editorial congratulated Texas governor Rick Perry for mandating “A Vaccine To  Save Women’s Lives.”(So far as I know, Merck makes no contributions to The New York Times, but Perry’s former chief of staff is a Merck lobbyist.) At this point, twenty states have drafted plans to follow Perry’s example.

Last summer, I wrote about the vaccine on American Prospect Online.At the time, I tried to make two points. First, while Merck’s vaccine could cost U.S. patients, insurers and state governments billions of dollars, it will not be saving millions of lives - because, in the countries where it will be available, there are not millions of lives to be saved.

In the U.S., we already have come close to winning the war on cervical cancer with the $30 Pap smear - a simple test that has proven remarkably effective. Thanks to screening, between 1955 and 1992 the number of cervical cancer deaths plunged by 74 percent, and the numbers are still shrinking. From 1997 to 2003, deaths fell by anaverage of 3.8 percent each year. In 2006, it’s estimated that cervical cancer will account for just less than one percent (.65% to be exact) of the anticipated 273,560 cancer deaths among American women...

Continue reading "Merck’s Miracle Vaccine –What Is This Story Really About?" »

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Passive immunization is the answer.
COLUMN by Jack Woodall
In 1942, long before the vaccine wasavailable, I contracted measles, went into a coma, but recovered. Myyounger brother and sister received transfusions of immune serum fromour mother, who had had measles as a child, and were protected. Mysiblings were not the only ones to benefit from serum treatment: In 1970, two people working on Lassa fever at a university research labcaught the illness, and one died. The other was diagnosed in time,received immune serum from a Lassa survivor, and recovered.

Vaccines have saved countless lives. But thereare still diseases that cause large numbers of cases and deaths, suchas dengue and malaria, for which vaccines have been sought for decadesbut always seem to be five years in the future. Other importantdiseases like Ebola and Lassa fevers are crying out for vaccines, whichare under development but still predicted to take years before theywill be generally available.Read more...Collapse )
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More than six-thousand students in the Marylandsuburbs of Washington were kept out of classes yesterday because theydid not have the proper record of vaccinations.

A law requiringstudents in sixth through ninth grades to provide records of chickenpoxand hepatitis B vaccinations took effect with the new year. The only exceptions were for those who had proof with proof of appointments to get the shots by January 22nd.

School officials say they've been working for months to get the word out, but some parents haven't paid attention. PrinceGeorge's County officials say more than four-thousand students weresent home. In Montgomery County, about 500 students took home anotherwarning letter from principals.

Frederick County had 327 children out of compliance; Saint Mary's County had 381 and Anne Arundel County had 993.

Continue reading "6,000 Md. students without vaccine records kept out of school" »


Hmmm... I dont like it, really. Who said "it's free country"?

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juliacw
immunodefence
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sanofiLet's see, Sanofi invests €160 million last year, then produces 170 million influenza shots this year. The price of a single shot varies between $10 and $15 (according to CDC). Gross profit would make $1.7 billion, at least. 800% ROI? Not bad. What was the key factor of this outcome? A fear. Consumers' fear.

Don't forget that some pharma companies were doubling the price (Some Suppliers Jack Up Flu Vaccine Price, The Washington Post, Oct.14, 2006). And now there's a huge surplus of influenza vaccines stocked in clinics. Will we see another warning about some new virus, dangerous and deadly, for sure?

Sanofi pasteur, the vaccines business of the sanofi-aventis Group (NYSE: SNY; EURONEXT: SAN), announced that it completed production of more than 170 million doses of influenza vaccine in 2006. Sanofi pasteur confirmed its leadership as one of the world’s largest manufacturers of seasonal influenza vaccine, supplying a very significant portion of the estimated global production of about 350 million doses.

As the global influenza vaccine leader, Sanofi pasteur has been steadily increasing its manufacturing capacity. Since 2003, capacity has increased by more than 40% in line with the company's commitment to serve a central role in the fight against a disease that causes between three and five million cases of severe illness and between 300,000 and 500,000 estimated deaths every year around the world according to the Word Health Organization. In addition, sanofi pasteur’s leadership position in developing and producing influenza vaccines places the company at the forefront of readiness against the threat of pandemic influenza. The company is committed to producing as many doses of sanofi pasteur’s most advanced vaccine in the shortest possible timeframe, should a pandemic be declared by the world's health authorities.


Continue reading "Sanofi Pasteur Influenza Vaccine Production Tops 170 Million Doses In 2006" »

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Another vaccine for newborns and infants? Sounds like a plan. A plan to fulfill another plan. Such as Pfizer's plan to increases the global vaccine sales to 30+ billion USD by 2015.
I can only hope that vaccinations won't be made obligatory worldwide. Though this hope may die by the time 2015 will arrive.

KANSAS CITY, Mo. -- Doctors said rotavirus is a contagious, gastrointestinal illness that is especially dangerous to infants.

Experts at Children's Mercy Hospital are encouraging parents to make sure their babies receive a new rotavirus vaccine as part of their immunization schedule.

Rotavirus is a common childhood illness, characterized by fever, vomiting and watery diarrhea. It can cause severe dehydration in infants and toddlers.


Continue reading "Doctors Suggest Infants Get Rotavirus Vaccine" »
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vaccine2006 was a very big year when it came to health news. New drug approvals, new vaccines, health scares that never quite made it and health scares that keep coming back for more. They were all part of the big year in health news in 2006.

2006 could easily be named the year of the vaccine. Several new shots hit the market: the first shingles vaccine, a whooping cough, or pertussis vaccine, for adults and a new, safer rotavirus vaccine to prevent the common diarrheal illness in children.

The biggest news, perhaps, surrounded the cervical cancer vaccine. It's approved for pre-teen girls to prevent HPV--human papilloma virus--the sexually transmitted virus that triggers cervical cancer.

Continue reading "2006 Could Be Called the Year of the Vaccine" »

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vaccineBEIJING, Dec. 18 (Xinhua) -- China is seeking volunteers to participate in its second clinic trial of a new AIDS vaccine early next year, a leading Chinese scientist said recently.

The center is looking for men and women to participate in the trials which will take place in Beijing, said Shao Yiming, chief expert for the National Center for AIDS/STD Control and Prevention. He revealed the plan at a conference on Sino-U.S. AIDS vaccine research and development held on Sunday without indicating how many participants will be involved in the trial.

The vaccine was approved for clinical trials by Chinese drug authorities in November. Trials on Rhesus Monkeys indicates that the vaccine is safe and effective in preventing HIV infections, Shao said.

InMarch of 2005 China began its first human clinical trials on an AIDSvaccine in southwestern Guangxi Zhuang Autonomous Region. Thevolunteers, 33 men and 16 women aged from 18 to 50, have beenvaccinated and none have had adverse side effects. According to a recent report, there are 120 clinical trials of AIDS vaccines being conducted on humans throughout the world.

TheMinistry of Health said that by the end of this October, a total of183,733 people had been officially reported to have contracted HIV,39,644 more than at the end of 2005.

(http://vaccine.immunodefence.com/2006/12/china_to_test_new_aids_vaccine.html)
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tetanus vaccineKozhikode, INDIA - Tetanus vaccination has been temporarily suspended following the death of Rupisha (15), daughter of Rajan of Kuttiyadi. A temporarily ban was put on the vaccine of Mumbai based Afkin Company which is suspected to be the cause of death of the girl. The health department ordered to suspend the vaccine used in the Vattoli sector.

Though the authorities stated that the death was not due to the tetanus vaccine, suspicion arose after temporarily suspending it. The sample of the medicine used for the tetanus injection at the Vattoli High School has been sent for analysis to the National Virology Institute at Hasoli in Himachal Pradesh. The decision to ban the injection temporarily was taken since it takes at least one month to get the report.
(Source)

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